Testosterone recuperates deteriorated male fertility in cypermethrin intoxicated rats

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Effects of cypermethrin on male reproductive system in adult rats.

OBJECTIVE To evaluate effects of cypermethrin on the testis histology and testosterone, LH and FSH in adult male Sprague-Dawley rats. METHODS The intact adult male rats were randomly divided into five groups and were treated with cypermethrin at doses of 0, 7.5, 15, 30, or 60 mg/kg per day by oral gavage for 15-days. After the treatments, serum was collected for hormone assays. The testes, ep...

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  Population explosion is one of the problems of developing countries today. This topic has been evaluated from different standpoints. From a family point of view a variety of contraceptive devices and medications have been devised and used. At present, the available mean in men is only vasectomy (surgical and non-surgical) barrier method (condom). Since the available methods and medications do...

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Exogenous Testosterone, Finasteride and Castration Effects on Testosterone, Insulin, Zinc and Chromium in Adult Male Rats

Background: Although effects of trace elements on secretion of sex steroids and insulin have been studied, the effects of these hormones on serum level of trace elements have been rarely investigated. The aim of the present study was to evaluate the effect of testosterone and finasteride administration and castration on serum levels of testosterone, insulin, zinc and chromium. Methods: Male adu...

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Troxerutin affects the male fertility in prepubertal type 1 diabetic male rats

Objective(s): Diabetes can gradually cause damage to the function and structure of male gonads. This survey was conducted to investigate the effect of troxerutin on hormonal changes, serum oxidative stress indices, and testicular function and structure in prepubertal diabetic rats.Materials and Methods: Fifty prepubertal (6 weeks old) male Wistar rats were divided into five groups including Con...

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Ameliorative role of melatonin against cypermethrin or gamma irradiation induced testicular damage in male rats

Background: This work aimed at studying the protective effect of melatonin (MLT) against cypermethrin or γ-radiation induced testicular damage. Material and Methods: Thirty six Male rats were randomly divided into 6 groups.  Control group, group treated with MLT (10 mg/Kg b. wt.), group administered cypermethrin (25 mg/ kg. b. wt.), group 4 was exposed to fractionated whole body γ-radiation (th...

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ژورنال

عنوان ژورنال: Toxicological Research

سال: 2020

ISSN: 1976-8257,2234-2753

DOI: 10.1007/s43188-020-00046-1